Determination of Methyl-, Chloromethyl- and Benzisothiazolinone in cosmetic products and fingerpaint using UPLC-MS-MS, versie 6

This procedure describes a method for the determination of methylisothiazolinone (MI), chloromethylisothiazolinone (CMI) and benzisothiazolinone (BIT) in (child) cosmetics and fingerpaint. The method is validated for a cream, liquid soap and a fingerpaint. The method is applicable for MI, CMI and BIT in the range of 0.8 – 160 mg·kg1.